Vasculitis can affect the peripheral nervous system without impacting the central nervous system (nonsystemic vasculitic neuropathy), or it can affect the peripheral nervous system as part of primary or secondary systemic vasculitis. In cases of pre-existing systemic vasculitis, the diagnosis is straightforward; however, suspected vasculitic neuropathy as the first or only sign of vasculitis demands a comprehensive clinical, neurophysiological, laboratory, and histological examination. The most prevalent clinical form is mononeuropathy multiplex or asymmetric neuropathy, but distal-symmetric neuropathy is also common. Common treatments include steroids, azathioprine, methotrexate, and cyclophosphamide. The B-cell antibody rituximab and intravenous immunoglobulins have recently been shown to be useful in some cases with vasculitic neuropathy.